This tutorial review provides a broad and accessible introduction to the field of cellulose, covering its sources, isolation methods, structural properties, and applications. The authors have assembled a significant amount of information and provided innovative considerations in fields like impurities in bacterial cellulose (BC). However, the manuscript exists logical inconsistencies and lacks substantive content relevant to the topic of green chemistry. Therefore, I recommend rejection and resubmission after a necessary major revision to meet the scope and quality standards of Green Chemistry. The detailed comments are as follows:
1. The information is sometimes confusing and hinders understanding. So the contextual logic of the manuscript should be conscientiously improved.
• It appears to have missing information in Section II, A, ii, as it only mentions IL-related information without DES mentioned in the title.
• Regarding the bacterial cellulose mentioned in section II, B. It comes from a synthetic pathway rather than separation, so it is debatable to discuss it in the “Cellulose Separation from Biomass Sources” section.
• The discussion regarding the cellulose dissolution in section II, C, i involves IL and DES while the title only mentions IL. It is recommended to discuss separately or improve the expression of the title.
• Several parts of the text only have one sub-number and they should be merged with the content of their higher-level heading. e.g., C, i, a (without b) in section II; B, i (without ii) in section IV.
2. The schematic figure should be improved to possess better scientific validity. e.g., Fig. 1 lacks the crystalline structure of cellulose and the interaction between the ionic liquid and cellulose; the comprehensive concept figure of the manuscript is recommended to be added to facilitate the reader’s understanding of the manuscript framework.
3. As a manuscript aimed at new researchers, some information needs to be expressed more rigorously and comprehensively.
• The cellulose dissolution systems contain not only IL and DES, but also alkali-urea system, traditional NMMO system, and Copper ammonia solution system, etc.
• Regarding the “drying nanocellulose suspensions” part, it seems that only the drying methods for preserving the porosity of nanocellulose aerogels have been discussed. However, the preparation of functional films and hydrogels using nanocellulose has also received widespread attention. The choice of drying method is not limited to preserving porosity but also involves adjusting the material's structure to exhibit different properties in mechanical, optical, and other fields.
4. The citation format needs further adjustment; several references are incomplete (Ref. 28, 138, etc.) or incorrectly formatted with the aimed journal.
5. There are treatment methods and evaluation principles in the field of cellulose separation or dissolution that meet the requirements of green chemistry. A targeted summary of these parts will make the manuscript more aligned with the journal’s topic.

I agree with the author's revision on this manuscript.