Content of review 1, reviewed on November 07, 2025

General comments:

  1. This is a well-written manuscript, showing AID systems can maintain excellent glycemic control during commercial flights. This data may be important for commercial flight pilots and their regulatory agencies. The results are not surprising, however, they are novel and important for aviation authorities.

Specific comments:

  1. This group of participants achieved very high TIR and TITR values and they are not representative of general population. However, pilots with diabetes need to achieve such excellent control with their diabetes, which serves the aim of the study.

Source

    © 2025 the Reviewer.

Content of review 2, reviewed on December 07, 2025

I have no further comments

Source

    © 2025 the Reviewer.

References

    Renald, M., Silvia, B., M., B. P., Monika, C., Omaima, E. H., A., H. D., Fariba, S., Siu, F. K., Dietrich, T., R., P. T., David, R., Chantal, M., Gerd, K., K., M. J. In-Flight Glycemic Control Using Automated Insulin Delivery Systems: A Within-Subject Comparative Pilot Study. Diabetes, Obesity and Metabolism.