This manuscript focused on the diagnostic values of bronchoalveolar lavage (BAL) for non-small cell lung cancer (NSCLC). Compared to tissue samples, BAL as the alternative of liquid biopsy demonstrated almost equal performance of gene mutation detection. Despite the limited number of clinical samples, the study claimed great promise for BAL feasibility in clinical diagnostics. Overall, the manuscript met the basic standard of TCRT.

Minor Comments:
1) More explanation about the less consistency of BAL to tissues in tier II & III could be added.
2) In the introduction part, the authors mentioned the utility of BAL extracellular vesicle (EV) for genotyping detection, but nothing related came out later. Although no EV experiments were conducted, the authors could have some discussion on this part, like comparison of BAL gene versus BAL EV gene, etc.

The manuscript was informative and well-corrected. I think it is ready to publish.