The revised manuscript has been divided into several parts and more detail of the work has been added into method and figure legends. All these efforts make the manuscript much easier to follow. By adding a key simulation that the using CM mechanism only, It becomes clearer now that the cell migration mechanism plays the most important role in regulating RGC mosaics.
Some of the points on the previous comments have been addressed in the introduction and discussion. In the point-by-point response, the authors answered almost all of the questions raised before. However, the main structure of it has not been changed much. I do agree that “the model should incorporate only mechanisms necessary to explain a given phenomenon – in order to limit its complexity and allow reliable interpretation of the results”, but it will make the model more biologically relevant if the simulation could take consideration of some of the key known factors. In general this work provide a new angle of looking into the development of retinal neurons, and I believe that the model could be useful for biologist in the future after further optimization.