Tweet Review
Content of review 1, reviewed on April 23, 2021
This is very clear manuscript. The major issue is understanding the mechanism. It is salient that predictors of APR are really predictors of two things. One element is APR and the other is likelihood of reporting it. This could be done by examining the predictors of APR in the zol arm (which will include both elements) and placebo arm (which will include mainly a self reporting element) and seeing if the predictors are different. Otherwise, this is an excellent paper.
Source
© 2021 the Reviewer.
Content of review 2, reviewed on August 27, 2021
Thank you for fully addressing the comments.
Source
© 2021 the Reviewer.
References
M., B. D., R., R. I., Nicola, N., K., E. S., Masataka, S., Toshitaka, N., Yasuhiro, T., L., S. A., Y., K. T., A., C. J. 2022. The Interaction of Acute-Phase Reaction and Efficacy for Osteoporosis After Zoledronic Acid: HORIZON Pivotal Fracture Trial. Journal of Bone and Mineral Research.
