Content of review 1, reviewed on January 08, 2014

Significance Comment

The authors have explained the phenomenon of oxidative stress, role of cellular parts in oxidative stress, hepatitis C virus and its associated proteins, and the defensive role of body against oxidative stress in an optimum detail. This information about reactive oxygen species can easily be understood and replicated. After reading the paper, one can easily concludes that the paper encourages readers to research in the field of hepatitis and its therapeutic strategies. Clarity of the paper is worthy of consideration.

Quality Comment

In my opinion, this review paper presents information about hepatitis C virus and the related phenomenon of oxidative stress in a good manner showing that the authors went through the topic in an impressive detail.

Summary

Oxidative stress usually results from the body’s work against reactive oxygen species. This process can be aggravated as a result of various bodily and environmental conditions. Viral infections such as those caused by hepatitis C can also cause increased problems of oxidative stress resulting in hepatic damage and reduction in body’s ability to treat the damage. These disorders can lead the cells toward cirrhosis and hepatocellular carcinoma in adults. I am owner of a medical blog and writing articles on medical related topics.

Source

    © 2014 the Reviewer (CC BY-SA 3.0).

References

    Zafar, P. U., Kaneez, F., Mohammad, A., Adeel, C., Adel, A., Ghazi, D., Ishtiaq, Q. 2013. Oxidative stress and hepatitis C virus. Virology Journal.