Content of review 1, reviewed on July 15, 2015

In their manuscript titled 'Multi-platform miRNA profiling of FFPE samples from Hepatoblastoma patients,' Leichter et al. describe tumor microRNA expression profiles of 13 cases of hepatoblastoma. The microRNA data was obtained using three different technologies. Besides hepatoblastoma researchers, findings of this study should be of broad interest to those investigating microRNAs/small RNAs because of the nature of specimens (formalin-fixed tissues, the most commonly available type of archived clinical material) and because of the study's focus on comparison of the three different microRNA quantification technologies.

However, in my opinion, most of the information provided in this manuscript, has already been published recently in Scientific Reports (5, article 10438, June 2015). I therefore do not see a reason to publish this manuscript.
Level of interest An article of limited interest
Quality of written English Acceptable
Statistical review No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests I declare that I have no competing interests.

Authors' response to reviews: (http://www.gigasciencejournal.com/imedia/5963146581888086_comment.pdf)


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Source

    © 2015 the Reviewer (CC BY 4.0 - source).

References

    L., L. A., V., P. R., J., S. M., R., E. M., Aniruddha, C. 2015. Multi-platform microRNA profiling of hepatoblastoma patients using formalin fixed paraffin embedded archival samples. GigaScience.