Content of review 1, reviewed on January 02, 2022

Expression analysis identified significant differentially expressed circRNAs (DECs) in comparisons between thermal treatments (41 DECs) and between genetic lines (117 DECs). No intersection was observed between the DECs and differentially expressed gene transcripts indicating that the DECs are not simply the result of expression changes in the parental genes. Comparative analyses based on the chicken microRNA (miRNA) database suggest potential interactions between turkey circRNAs and miRNAs. Additional studies are needed to reveal the functional significance of the predicted circRNAs and their role in muscle development in response to thermal challenge. The DECs identified in this study provide an important framework for future investigation. Brief overview of the paper and its main findings

Please provide a brief overview of the paper and its main findings.

Major and minor points

This should be the main substance of your review and should bring up any weaknesses, inconsistencies, things that need to be clarified or questions you have for the authors.

Conflicts of interest

Do you have any conflicts of interest here?

Source

    © 2022 the Reviewer (CC BY 4.0).

References

    M., R. K., M., M. K., E., A. J., G., V. S., M., S. G. 2021. Data Mining Identifies Differentially Expressed Circular RNAs in Skeletal Muscle of Thermally Challenged Turkey Poults. Frontiers in Physiology.