Methods paper aimed at evaluating drug safety and efficacy of "Winniecure", a local therapeutic alternative to regularly-prescribed antiretroviral therapies (ART) for the management of HIV/AIDS. Work comes amid beneficial claims and toxicological concerns raised by end users.

Here's my take:

The paper is generally well-presented, with some few lapses though. At first glance, one could conclude that the "methods" section of the abstract was missing whereas, it was merged with the "background." I do agree with authors' spotting of some major flaws in the designing of the research which are: the non-comparison of Winniecure with conventional ART, and the absence of a surrogate marker like CD4 or viral load that are used to measure disease progression in HIV/AIDS. I would equally add that studies in the field of HIV/AIDS and more specifically those of this nature usually take into consideration the socio-economic background of the study participants, as these parameters greatly influence the study outcomes.Research in the field of HIV/AIDS is constantly evolving; nevertheles, a handful of the consulted works date back beyond a decade. Overall, the methods are well-described and executed with conclusions that are supported by authors' findings and those of earlier studies.