This manuscript summarized development of COVID-19 treatment, and pointed out drugs for treatment of the disease, especially Thalidomide. The authors therefore suggest the potential using of drug(s) for COVID-19. However, the author did not explain current situation of other drugs, especially chloroquine/hydroxychloroquine in this manuscript. In addition, no explanation of drug (A, B, or C) that suitable for use in combination with Thalidomide is available. This manuscript needs revisions as suggested above.

Line 39: “anti-viral molecule”: do you mean a drug? If an anti-viral drug is unavailable, why do you propose this drug to be combined with Thalidomide?

Line 60: “in 2012(Jin et al. 2020).” It should be “in 2012 (Jin et al. 2020).” Check entire the manuscript regarding the same errors.

Add recent information in lines 63-64 regarding the number of sufferers and deaths caused by COVID-19 all over the globe.

Add more information for chloroquine/hydroxychloroquine in lines 122-134. For example, see doi:10.20944/preprints202005.0057.v2.

Add at least one drug (anti-viral molecule?) for combination with Thalidomide in lines 297-303.