In terms of methodology, the sequence was scientifically valid. The initial draft though had certain gaps that were answered subsequently. However, there are limitations. University students, instead of actual CKD patients were the subjects of the study. Therefore, the frequency of symptoms maybe significantly less than patients with the disease. Applicability to early stage ckd and those non-compliant dialysis patients may also Be a concern. But overall, it answered its primary objective and hoping that a follow-up study be made on actual CKD patients.