Content of review 1, reviewed on August 11, 2020

The research aimed at testing antimicrobial and antifungal efficiency of selected Essential oils against drug-resistant strains. The results of MIC and MBC revealed that the essential oils extracted from medicinal plants distributed in the Asir district of Saudi Arabia have potent antibacterial and antifungal activity. The variation in zone inhibition obtained by the disc diffusion method has shown that gram-positive bacteria are more susceptible to essential oils compared to gram-negative bacteria. Based on the results it is evident that the essential oils belonging to the family: Lamiaceae are most active against bacteria and fungi. The chemical composition of essential oils of most active plants was determined by GC-MS. This research article addressed about antibiotic resistance crisis which is one of the biggest threats to health. Although essential oils of plants have antimicrobial activity, the research is scarce hence it is noteworthy to carry out such research. This article definitely made a mark in the field of herbal drugs and it gave an idea of how essential oils can be promising antimicrobial agents. Based on the results provided in this article, research can be carried out on the effective ways of administration of essential oils i.e, topical or oral. By confirming the chemical composition and establishing the mechanism of action the essential oils can be a promising alternative to the current synthetic antibiotics/ antiseptics.

Major points in the article which need clarification, refinement, reanalysis, rewrites, and/or additional information and suggestions for what could be done to improve the article.
1. Results and Discussion were kept before materials and methods.

Minor points like figures/tables not being mentioned in the text, a missing reference, typos, and other inconsistencies. 1. In the aim, it was not mentioned about the fungicidal activity.
2. The title of the research is relevant to the work done and in the title, the word “Against” will be more apt over the word “over”.

Source

    © 2020 the Reviewer.

References

    M., H. I., Ashraf, E., Erwa, A., P., J. M. R., Prasanna, R., C., C. H., Hadj, A. S. B. 2019. Antimicrobial Efficiency of Essential Oils from Traditional Medicinal Plants of Asir Region, Saudi Arabia, over Drug Resistant Isolates. BioMed Research International.