The paper is all about enumerating the seven candidate routes, which the mature or immature SARS‐CoV‐2 components could use to reach the CNS and PNS, utilizing the within‐body cross talk between organs. The paper also try to cover how the viral particles and/or its components have been specifically documented in endothelial cells of lung, kidney, skin, and CNS.

As a weakness , the paper is somehow crowding and bulky enough to make people understand easily. The authors declare that there are no conflict of interest.