In this review, the author presents five cases of large-vessel stroke in patients younger than 50 years of age who presented during the peak of the pandemic in NYC hospital with stroke symptoms and were subsequently also found to have Covid-19 infection. The author presents the clinical characteristics of these patients.

The article was published early during the pandemic in March 2020 and sheds light on the possible etiology of stroke among young patients with COVID, though given it is a small case series it should be viewed as observations, not an association. Major points in the article which needs clarification, refinement, reanalysis, rewrites, and/or additional information and suggestions for what could be done to improve the article.

1. Please present data on the incidence of stroke among all patients with COVID admitted at your hospital. How many patients with COVID were admitted during this time frame at your hospital and how many had a stroke?
2. How about those greater than 50 years? What was the presenting feature in those patients? What made the author conclude this is the only presenting feature among young?
3. Is it possible to include radiographic involved data for each patient? This would help the reviewer to assess the stroke volume because of large vessel occlusion.