Content of review 1, reviewed on May 19, 2020

Comments on abstract, title, references

title: "Predictors of Mortality in Staphylococcus Aureus Bacteremia" Comment: Aureus is written aureus

Abstract section: " Summary: Staphylococcus aureus bacteremia (SAB) is an important infection with an incidence rate ranging from 20 to 50 cases/100,000 population per year. Between 10% and 30% of these patients will die from SAB. Comparatively, this accounts for a greater number of deaths than for AIDS, tuberculosis, and viral hepatitis combined. Multiple factors influence outcomes for SAB patients".

1-Comment: the abstract should be separated into background, aims, conclusion

2-This abstract has no aims
the references not ordered

Comments on introduction/background

Introduction section: 3-" The incidence of SAB is generally higher for males than for females (143, 160). " Comment: the references not ordered
Comment: Introduction very long and have more items

Comments on methodology

Age (host factors) is the most consistent and strongest predictor of all-cause and infection-related 30-day mortality, with the majority of SAB cohort studies using multivariate analysis, confirming age as an independent predictor of mortality" Comment: the age group of children very susceptible to any type of bacteremia

5-"table 1 Summary of studies that have examined the impact of age on mortality in cases of Staphylococcus aureus bacteremia" Comment: Table 1 have a short name within the table: this is not correct

Comments on data and results

Fig 1Impact of age on overall 30-day mortality from Staphylococcus aureus bacteremia. Percentages of patients who succumbed at 30 days following an episode of Staphylococcus aureus bacteremia are stratified by 10-year age groups. (Adapted from reference 155 with permission of Elsevier". Comment: Fig 1 not clear and has no more title for columns

7-"table 2 All-cause mortality for patients with Staphylococcus aureus bacteremia stratified by the source of infection Comment: Table 2 was not cleared

8- "Gender: The incidence of SAB is generally higher for males than for females (143, 160). Despite this, several studies have shown an increased mortality rate for females. In several retrospective cohort studies of MRSA-B episodes, female gender was an independent predictor of 30-day all-cause mortality". Comment: gender was not important in this disease

9-"table 3 Summary of studies that have examined the impact of severity of illness on mortality in Staphylococcus aureus bacteremia " Comment: Table 3 have a short name within the table: this is not correct and it was not cleared

10-"Socioeconomic status (SES) is known to impact a patient's infection risk " Comment: Socioeconomic status was not important in this bacteremia

11-"table 4 Summary of studies that have examined the impact of methicillin resistance on mortality in Staphylococcus aureus bacteremia " Comment: Table 1 have a short name within the table: this is not correct it was not cleared

Comments on discussion and conclusions

discussion Comment: it is good discussion and covered all results with perfect idea

conclusions" Comment: This paper has no conclusions

Source

    © 2020 the Reviewer.

References

    J., v. H. S., O., J. S., L., V. V., A., E. B., L., P. D., B., G. I. Predictors of Mortality in Staphylococcus aureus Bacteremia. Clinical Microbiology Reviews.