The authors report on a neocentric sSMC(9); according to what they find they suggest that they identified a crtitcal region for patients with +inv dup(9) syndrome. Still there are (also at time of publicationof this paper) several reports in the literature with whole arm teratsomies of chromosome 9p which show a normal phenotype. So the conclusions should be made more carefully. Mosaicism and other factors ('genetic background'/ epigenetics) seem to play a role as well here.