see attached pdf
-- Matt MacManes
Level of interest An article of outstanding merit and interest in its field
Quality of written English Acceptable
Statistical review No, the manuscript does not need to be seen by a statistician.
Declaration of competing interests I declare that I have no competing interests.

The full text review can be found here: (http://www.gigasciencejournal.com/manuscript/review/attachment/6814043131769296.pdf)

Authors' response to reviews: (http://www.gigasciencejournal.com/imedia/1601647730184666_comment.pdf)

The reviewed version of the manuscript can be seen here:
http://www.gigasciencejournal.com/imedia/4199342441745773_manuscript.pdf
All revised versions are also available:
Draft - http://www.gigasciencejournal.com/imedia/4199342441745773_manuscript.pdf

Thanks to Li and Liliana for satisfactorily addressing my concerns. This is an very nice manuscript and I look forward to using the software.
Signed, Matt MacManes
Level of interest An article of outstanding merit and interest in its field
Quality of written English Acceptable
Statistical review Yes, and I have assessed the statistics in my report.
Declaration of competing interests I declare that I have no competing interests' below.

The reviewed version of the manuscript can be seen here:
http://www.gigasciencejournal.com/imedia/1238600626184671_manuscript.pdf
All revised versions are also available:
First revision - http://www.gigasciencejournal.com/imedia/1238600626184671_manuscript.pdf