International Journal of Food Science and Technology

IJFST-2022-35536

Holothuria scabra Jaegar 1833 (Sandfish) extracts and collagens modulate protein-bound Nε-carboxymethyllysine, Nε-carboxyethyllysine and methylglyoxal-derived hydroimidazolone-1 levels

Dear Prof. Charles Brennan,
Editor

First of all, I am really sorry to send my report late. Please forgive me!

The article deals with the evaluation sea cucumber (Holothuria scabra; Jaegar 1833) extracts and collagens for inhibitory properties of protein-bound advanced glycation end-products (AGEs). The topic is really good. In addition, this manuscript has been generally well designed and written. It can be accepted after the necessary corrections are done. The major thing is the discussion section is little bit poor. Therefore, discussion section should be improved. My specific comments and questions are appended below;

• Page 4, lines 26 and 27: ie?
• Material and method section should be extended! Because material preparation is not clearly understood.
• The authors should give all calculation formula in the material and methods section!
• Which one of the Figures is Fig 1? It is not mentioned!
• Did the researchers determine some properties (protein, pH etc.) of the samples?
• There is no any information about the method validation parameters for the analysis, especially for the chromatographic analysis

Dear Editor,
The authors have revised and improved their manuscript according to the reviewers' comments and suggestions. Therefore, the manuscript can be accepted and published in its current form.
Best regards,