This manuscript provides data for the hepatoprotective effects of curcumin up on copper oxychloride subchronic exposure in male albino rats few selected biochemical markers of oxidative stress has evaluated. In my opinion the study has some new useful data for copper oxychloride induced hepatotoxicity and protective effects of curcumin but i have some points which authors needs to address.

Background: 1) Author has written "The active portion of curcumin is turmeric" it would be "the active portion of turmeric is curcumin"

Material and methods: 1) Author has not elaborate the methodology portion. 2) Author has not mentioned about the protein estimation. How they have normalize mda and gsh level.

Discussion: Author has written discussion very nicely.

Reference: 1) Author has written abbreviated form of journal name instead of full journal name (Nnorom, I. C., & Ewuzie, U. (2015). Comparative study of trace metal (Cd, Cr, Cu, Fe, K, Mg, Na, and Zn). Asian J Plant Sci Res, 5, 22–29.)

2) Author has not written page no. in this reference (Doudi, M., & Setorki, M. (2014). Acute effect of nano-copper on liver tissue and function in rat. Nanomedicine Journal, 1.)