Content of review 1, reviewed on April 30, 2020

Review Comments: 1-Quote ”The plasma of recovered patients can be used to treat the severely ill COVID-19 patients as it contains the antibodies developed by the body in response to the viral infection. It was tried earlier for SARS and doctors were successful in improving the condition of some patients (34) whose condition continued deteriorating despite treatment with methylprednisolone. Shorter hospital stay and lesser mortality rates were observed for the patients treated with CP as compared to the patients without receiving it (35). Similar resorts were employed for Ebola in the year 2014 (36) and MERS patients in the year 2015 (37). Therefore, it would be worthwhile to test the efficacy of CP taken from the recovered patients on the COVID-19 patients”. End of Quote.

The authors have a valid point here. life expectancy has raised. If this is true then we should used some solutions for improving the efficacy of treatment COVID-19. and it might be in the good interests of the people of the World to let the good happenings.

2-Quote ”However, there are various downsides to this approach which includes the difficulty in scaling up for widespread use as well as the risk of transmission of other diseases that would come along with the plasma of recovered patients. Also the antibodies present in the plasma generally are in lesser concentration that may not be sufficient for the treatment. Regeneron company from US is about to introduce two antibodies that could act against COVID-19 which can be synthetically produced and their clinical trial would be started later. This would be helpful as both prophylactic and as a treatment measure especially for high risk groups”. End of Quote.

There seems to be some unexpected, we should reconsider some solutions for Treatment.

Source

    © 2020 the Reviewer (CC BY 4.0).

References

    Waquar, A., Shamama, J., Mohammed, A. B., A., A. H., Asim, N. 2020. Treatment of SARS-CoV-2: How far have we reached?. Drug Discoveries & Therapeutics.