Content of review 1, reviewed on May 19, 2020

Current Research in Nutrition and Food Science – Review Form

Title: Biochemical Alterations Accompanied to Zoledronic Acid Treatment after High Doses of Vitamin D in Experimental Model ID: FOOD_2696

Conflict of Interest: None exists Please check the review policy at www.foodandnutritionjournal.org/submission/review-guidelines/ Does the paper meet a high standard of scientific quality and credibility?Yes No NO Is the paper readable and appropriately presented?Yes No NO English language level: is the English language comprehensive and flawless?Yes No NO Are there any grammatical or spelling mistakes?Yes No YES Are full forms for abbreviations stated at the 1st mention of the abbreviation? Yes No YES Are appropriate legends provided with tables/ figures? Yes No YES Does the paper contain appropriate referencing?Yes No Does the paper contain any recognizable plagiarism?Yes No NONE NOTED THOUGH NOT DETERMINED WITH ANY PLAGIARISM TEST SOFTWARE Level of Interest: Please indicate how interesting you found the manuscript. As written, not interesting. The manuscript could be improved by justifying the study aim appropriately in the introduction section and discussing the study results in line with the justified study aim as designed.

Does the paper compliant with the aims and scope of the journal it is submitted to? Yes No POTENTIALLY Does the paper meet ethical requirements?Yes NoYES Does the paper include animal or human study? If yes, was ethical committee approval details provided in the paper? Yes NoNot Applicable YES Is this a human intervention study? Was consent taken before the study? Yes NoNot Applicable Is the statistical analysis sound and justified? (Does it require expert statistical review?) Yes NoYES

Other Comments? The study as written was not well-coordinated. There is need to reorganize the study report to achieve coherence in study aim, introduction, design, discussion and conclusion. For instance, the introduction failed to justify the study need for the study aim suggested from the title. The seeming confusion on the study aim portrayed in the introduction was manifested in the discussion section and conclusion.

Comments per section of manuscript:

Abstract As in the attached Introduction As in the attached and in above Methodology As in the attached Results and Discussion As in the attached References (Appropriateness) -

Rating (1 to 5) 5: Excellent, 1: Poor

Originality 3 Depth of research 4 Technical quality 2

Recommendation:  Reject unconditionally

 Reject in current form, but allow resubmission after revision as per my accompanying comments

 Accept conditionally, subject to minor revision, according to my accompanying comments

 Accept unconditionally

Reviewer Name: Anthony Cemaluk C. Egbuonu, Ph.D Designation:

Address : Department of Biochemistry, Michael Okpara University of Agriculture Umudike, Nigeria Date:

19/05/2020 Research Interest: Nutritional Biochemistry, Natural Products, Toxicology, Pharmacology, Molecular Biology

Publons ID: https://publons.com/researcher/1201611/anthony-cemaluk-c-egbuonu/

ORCID ID: https://orcid.org/0000-0001-5974-415X Signature: ACCE

Source

    © 2020 the Reviewer (CC BY 4.0).

References

    Abdel, M. H. A., G., E. M., H., A. M., R., A. K., A., A. N. 2020. Biochemical Alterations Accompanied to Zoledronic Acid Treatment after High Doses of Vitamin D in Experimental Model. Current Research in Nutrition and Food Science Journal.