valuable finding that the MHAE has an antiulcer effect against ethanol-induced gastric lesions in experimental rats. The gastroprotective effect of this potent medicinal plant could be associated with its free radical-scavenging activity, its ability to increase the endogenous activities of SOD and CAT antioxidants while reducing the level of MDA, and its ability to upregulate Hsp70 and downregulate Bax protein. The gastroprotective role of the MHAE could also be due to its stimulation of an anti-apoptotic pathway.