Neuroimaging, including computed tomography (CT) and magnetic resonance imaging (MRI) are frequently performed in patients who present with status epilepticus (SE). Here we discuss the role of these neuroimaging modalities in clinical evaluation and seizure localization. Additionally, translational neuroimaging research and advanced imaging technologies, such as perfusion and radionucleotide imaging may also contribute to localization of the seizure onset zone and yield opportunities to better understand the pathophysiology of SE and aid in prognostication.