Background: No study has examined dopamine D-2/3 receptor (D2/3R) availability in antipsychotic-free older patients with schizophrenia.Methods: We included patients with schizophrenia 50 years or older who were antipsychotic-free for at least 3 months. We compared non-displaceable binding potential (BPND) of [C-11]-raclopride in the caudate, putamen, ventral striatum, and globus pallidus between patients and age-and sex-matched healthy controls.Results: Ten patients participated (antipsychotic-naive = 4). No differences in BPND were found between patients and controls in any ROIs (F(1, 72) = .42, p = .52).Conclusion: The preliminary results suggest no differences in D2/3R availability between antipsychotic-free older patients with schizophrenia and controls. (C) 2015 Elsevier B.V. All rights reserved.