1974 – High School Degree (Classical Studies) in Aversa (Caserta); 1979 – Research project concerning his Thesis, at the Dept. of Chemical Pathology, Whittington Hospital, London, UK (Chair: Prof. T.L. Dormandy); 1980 – Degree in Medicine and Surgery cum laude at the Univ. of Siena, Italy, with a Thesis in General Pathology on the pathogenesis of Neuronal Ceroid-Lipofuscinosis (Supervisors: Prof. M. Comporti, Prof. G.C. Guazzi); 1984-1987 – Ph.D. Course ('Dottorato di Ricerca') in Experimental and molecular Pathology at the University of Turin, Italy (Supervisor: Prof. M.U. Dianzani); 1988 – Ph.D. Thesis on the pathogenic mechanisms of hepatic and extrahepatic injury induced by bromobenzene; 1990 – Research project on glutathione conjugates, at the Dept. of Biochemistry, University College and Middlesex School of Medicine, London, UK (Chair: Prof. Brian Ketterer); 1992 – Following a national selection, is appointed Associate Professor of General Pathology at the Faculty of Medicine and Surgery of the University of Siena; 1993 – Research project on histochemistry of oxidative stress, at the Lab. of Histology and Cell Biology, University of Amsterdam, The Netherlands (Chair: Prof. J.C.F. Van Noorden); 1994-97 – Responsible of a research unit included in the National Project “Biology and Pathology of the Cell Cycle” (Funds provided by the Italian Ministry for University and Research); 1996–2000 - President of the University Course for Biomedical Technicians, University of Siena; 1998-2003 – Research grant from the Associazione Italiana per la Ricerca sul Cancro (Milan, Italy); 1999 – Member in the European Committee of the Society for Free Radical Research; 2000 – Visiting Professor at the Fac. of Pharmacy, Université Henri Poincaré Nancy, France; 2000 – Appointed Full Professor of General Pathology at the Faculty of Medicine and Surgery, University of Pisa, Italy; 2002-2004 – Research project supported by the Italian Ministry for University and Research (FIRB-2001 Funds); 2005-2006 and 2009 – Research grant from the Italian Cystic Fibrosis Foundation (Verona, Italy); 2008-2011 - Research grant from the Istituto Toscano Tumori (ITT, Firenze, Italy); 2008-2011 - Ceo at SORTA Srl.-a University of Pisa Spin-off ( www.sorta-biomedical.com )
Prof. A. Pompella is author of over 135 papers, published in international peer-reviewed scientific Journals, 3 international patents and approx. 120 presentations at national and international congresses; in particular, to date his publications have received over 7000 citations (Scholar H index = 40). Has served as Reviewer for Journals as Biochemical Pharmacology, Biochimica et Biophysica Acta, Free Radical Biology and Medicine, Pharmacology, Archives of Biochemistry and Biophysics, Brain Research, FASEB Journal, as well as for the Wellcome Foundation. Is member of the Società Italiana di Patologia e Medicina Traslazionale, the Society for Free Radical Research (SFRR) and the Society for Histochemistry. During the period 1998-2000 has been elected in the European Committee of the SFRR. Starting in 2002 has been appointed Associate Editor of the Journal Archives of Biochemistry and Biophysics. In Spring 2003 has served as Referee for the Research Funding Program of the Greek State Council for Science and Technology (CRST). Since 2007 participates as Foreign collaborator in a research Project funded by ISTC (Moscow) and based at the University of Yerevan, Rep. of Armenia.
Research activity of Prof. Pompella has been dedicated to molecular mechanisms, histochemistry and pathophysiologic effects of oxidant stress and lipid peroxidation, with special reference to the role of glutathione and glutathione-related enzymes. His studies were concerned with the identification in vivo of products of lipid peroxidation, the pro-oxidant effects of membrane-bound gamma-glutamyltransferase activity, protein S-thiolation and the mechanism of anticancer drug resistance.
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